Solution structure of a protein denatured state and folding intermediate
Article Abstract:
The solution structure of a true denatured state is solved by nuclear magnetic resonance under conditions that would normally favor folding, while its equilibrium and kinetic behavior is studied. A mutant of Drosophila melanogaster Engrailed homeodomain that folds and unfolds reversibly just by changing ionic strength.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Lethargus is a Caenorhabditis elegans sleep-like state
Article Abstract:
Studies related to sleep-like quiescent behavioral state called lethargus observed in arthropod Drosophila melanogaster and nematode Caenorhabditis elegans are described. The findings identified the cGMP-dependent protein kinase gene egl-4 as a regulator, which promoted the sleep-like behavior.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
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Mechanism of coupled folding and binding of an intrinsically disordered protein
Article Abstract:
The article explains the methods used and the processes involved in examining the folding and binding of disordered proteins in intermolecular interactions.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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